Category: beta-Cryptoxanthin >Buah Merah >Buah Merah 500 >BUah Merah 500VE >English >Indonesia >lung cancer >Osteoporosis >Papua

Buah Merah and Papua People (4): Significant value of Buah Merah

05/23/2013 13:29

Buah Merah and Papuan People

by Mathelda Kurniaty Roreng, S.TP, M.Si
and Toshiaki Nishigaki, Ph.D

Nutrition Values of Buah Merah

There are documentations and published books on nutritional analyses of Buah Merah extract in Indonesia.
We had questions on those data and could not trust them.

Complete analyses of high quality Buah Merah oil were conducted at reputable laboratories in Japan, outsourced by M&K Laboratories Inc.
The quantitative analysis method of carotenoids in Buah Merah oil has been developed and analyzed by co-working team of Faculty of Pharmacy, Nagasaki University, headed by former vice-president of the University, Prof. Dr. K. Nakashima (he is now Professor of Nagasaki International University).


Dinner with Buah Merah


Enjoying Bakar Batur dish with Buah Merah source

From these results, Buah Merah oil is rich in carotenoids, lipids and vitamin E. All are lipids and lipid soluble ingredients.

The contents of proteins, carbohydrates and minerals are scanty. Total carotenoid level is more than 200mg/100g.
Vitamin E is about 20mg/100g that is the highest among oils extracted from any other fruit meats.
It was found that Buah Merah oil contains 4 types of carotenoids; alfa-carotene, beta-carotene, alfa-cryptoxanthin and beta-cryptoxanthin. Among them, beta-cryptoxanthin level is the highest.
This is the first evidence that Buah Merah contains alfa-cryptoxantin and beta-cryptoxanthin.

Fatty acid analyses of Buah Merah oil disclosed that fatty acid constituents resemble to those of animal fats and no trans-fatty acids are not found (9).

Thus, Buah Merah is good sources of pro-vitamin A carotenoids, vitamin E and lipids  which can be comparable to animal fats because of similar fatty acid compositions.
The lipids of Buah Merah oil may enhance absorption of carotenoids from the guts without additional ingestion of oil.

Buah Merah oil can be extracted from oil droplets of cellular matrix without use of any synthetic chemical and at low temperature.
We recognize Buah Merah oil as purely natural food comparable with fruit itself.

Buah Merah oil is a unique, natural food to provide 4 kinds of carotenoids and fruit oil.


Book on Buah Merah, Indonesian version

cover page of BM book

Book on Buah Merah, Japanese version


1 R Otsuka. Earth of Mongoloids (2) Encounter to South Pacific Ocean (in Japanese),  Tokyo University Publication, Japan, 1997

2 N Fukui et al. What is Human History vol. 20 (in Japanese), Kodansha, Japan, 2009

3 K Muller. Introducing Papua. Daisy World Books, Indonesia, 2008

4 J Pasveer. Prehistric Human Presence in Papua and Adjacent Areas, The Ecology of Indonesia Series vol. VI : The Ecology of Papua Part One, by AJ Marshall and B M Beehler. Periplus Editions (HK), edited. Singapore, 2007

5 T Nishigaki and K Nakashima. Buah Merah (in Japanese), Ikuhosha, Japan, 2007

6 T M Nishigaki and I S Waspodo. Buah Merah (in Indonesian), Yayasan Pengusaha Makanan dan Minuman Seluruh Indonesia, Indonesia, 2007

7 The Division of Balance Sheet of Regional and Cross-Sector Anakysis. Papua in Figure 2011, BPS-Statistics of Papua Province

8 RJ Johns, GA Shea, W Vink and O Puradyatmika. Montane Vegetation of Papua,  The Ecology of Indonesia Series vol. VI : The Ecology of Papua Part Two, edited by AJ Marshall and B M Beehler. Periplus Editions (HK),. Singapore, 2007

9 Internal Archives of M&K Laboratories Inc. Japan

10 T Nishigaki, F N A Dewi, H Wijaya and H Shigematsu.  Acute and Subacute Toxicity Studies of Pandanus conoideus (Buah Merah) Extract Oil in Sprague Dawley Rats. Internal Archives of M&K Laboratories Inc. Japan

11 T Maeda, H Miyakita, M Goto and A Ito. Mutagenicity Study (of Buah Merah Oil Made by PT Papua Herbal Sejahtera, Indonesia), Internal Archives of M&K Laboratories Inc. Japan

12 Micronutrient Information Center, Linus Pauling Institute, Oregon State University. http://lpi.oregonstate.edu/infocenter/phytochemicals/carotenoids/index.html#biological_activity

13 Redaksi trubus. Panduan Praktis BUAH MERAH (in Indonesian), 2005, Penebar Swadaya, Indonesia.

14 H Wijaya and T Nishigaki. Preliminary Pharmacokinetic Study of Buah Merah oil in healthy humans. Internal Archives of Center for Agro-Based Industry, Ministry of Industry, Indonesia

15 Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, sikicon, vanadium and zinc. 2001, National Academy Press, USA

16 T Tanaka et al. Suppression of Azoxymethane0induced colon carcinogenesis on male F344 rats by Mandarin juice rich in b-Cryptoxanthin and Hesperidin. Int. J. Cancer: 88, 146–150 (2000)

17 C Liu, RT Bronson, RM Russel and XD Wang. β-Ctryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage and squamous metaplasia in ferrets. Cancer Prev Res, Published online March 18, 2011

18 S Uchiyama, T Sumida and M Yamaguchi. Oral Administration of  β -Cryptoxanthin Induces Anabolic Effects on Bone Components in the Femoral Tissues of Rats in Vivo. Biol. Pharm. Bull. : 27(2) 232—235 (2004)

19 Winarto, M Madiyan and N Anisah. The effect of Pandanus conoideus Lam. Oil on pancreatic β-cells and glibenclamide hupoglycemic effect of diabetic Wistar rats. Berkala Ilmu Kedokteran: 41 (1) 11-19, 2009

20 IM Budi and F Paimin, Buah Merah (in Indonesian), Penebar Swadaya, Indonesia, 2004

21 M Yahya and BTW Wiryanta. Khasiat & Manfaat Buah Merah (in Indonesia). AgroMedia Pustaka, Indonesia, 2005

22 Redaksi AgroMedia. Pro & Kontra Buah Merah. AgroMedia Pustaka, 2005

23 T Nishigaki, K Hirose, IS. Surono and H Shigematsu.  Antitumor Effects of Pandanus conoideus in in vitro and in vivo Studies. Internal Archives of M&K Laboratories Inc. Japan

24 T Nishigaki and K Hirose. In vivo-growth inhibition of human gastric cancer K-MK-6

by Buah Merah. Internal Archives of M&K Laboratories Inc. Japan

25 H Yoshitomi, T Nishigaki, I Surono and M Gao. Longevity of Spontaneous Hypertensive Rat-Stroke Prone Rats (SHR-SP) by Morinda citrifolia (Noni) fruit juice, Cocos nucifera (Extra Virgin Coconut Oil ) and Pandanus conoideus (Buah Merah) oil. International Conference, Exhibition and Short Course on Nutraceuticals and Functional Foods in Indonesia, October 11-15, 2010

26 M Hatai, H Yoshitomi, T Nishigakiand M Gao. Inhibitory Effects and Mechanism of Buah Merah (Pandanus conoideus) Oil on Melanogenesis. Japan Pharmacy Conference, supposedly held in Shizuoka in April, 2011. Buah Merah Meeting in Tokyo, May 15, 2011

27 M Hatai, H Yoshitomi, T Nishigakiand M Gao. Stimulatory Action of Tyrosinase Degradation by Buah Merah Oil. Japan Pharmacy conference, March, 2012

28 F Lian, KQ Hu, RM Russel, XD Wang. 2006. beta-Cryptoxanthin suppresses the growth of immortalized human bronchial epithelial cells and non-small lung cancer cells and up-regulates retinoic acid receptor beta expression. 2006, Int. J. Cancer. 119:2084-2089.

Buah Merah 500VE is typical Buah Merah oil capsule product launched in Japan.


As of now, Buah Merah 500 /500VE capsule products have not been available 
in any other country except Japan.
We are willing to send Buah Merah 500VE on request of readers from any country.
It is said that you can purchase food supplements for your self consumption without permission of authority.

Three (3) bottles of Buah Merah 500VE are ready to send you by EMS.
The price including EMS charge is USD 180. 
Remittance cost is considered to be minimal.

Buah Merah 500VE is good for 
fanatic smokers, patients with cancers, DM, post-menopausal oesteoporosis, 
acne, boldness, malnutrition and other serious diseases, 
and for enhance of your health, longevity.

Please contact, Dr. M. Nishigaki, 



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